Avidity measurements of specific cell surface receptors
The CellVysion does have two channels with a gradient of ligands each. This allows the determination of avidity of - for example - antibodies vs. cells.
Hence, a new avidity parameter is introduced by applying the CellVysion. The ligand density at the tipping point after cell binding and controlled shear conditions is typical for a certain combination of anti-cell receptor antibodies with a certain cell line. The instrument is capable of determining this tipping point accurately.